A radiomics-based decision support tool improves lung cancer diagnosis in combination with the Herder score in large lung nodules.

6 of these features were highly significant (p < 0.001, Wald test) after correction for multiple testing, and were selected for the multivariable model: Brock score, Herder score, a history of lung disease, a history of extra-thoracic malignancy, nodule density and PET avidity.

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