Alfaxalone population pharmacokinetics in the rat: Model application for pharmacokinetic and pharmacodynamic design in inbred and outbred strains and sexes.

Pharmacol Res Perspect · 2022 · PMC9667119 · PMID 36380704

Europe PMC DOI

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highly significantno p-value reported

NLME models for populations 1 and 2 exemplify the sex difference in alfaxalone clearance where in both cases sex is a highly significant covariate.

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