Barely Significant
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Herpes simplex virus 1 protein pUL21 alters ceramide metabolism by activating the interorganelle transport protein CERT.

J Biol Chem · 2022 · PMC9668737 · PMID 36243114

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highly significantno p-value reported
Furthermore, we observe a highly significant increase in the abundance of labeled Cer when cells are infected with HSV-1, this increase being greater when pUL21-mediated CERT activation has been abolished.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.