Epidemiology of liver cirrhosis and associated complications: Current knowledge and future directions.

A recent study that included patients with a primary diagnosis of HRS in the NIS from 2008-2018 found a notable increase in the number of HRS hospitalizations from 22864 in 2008 to 42985 in 2018; however, there was a decreasing trend in inpatient mortality (36.2% in 2008 to 25.7% in 2018)[ 105 ].

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During this period, 165979 cases of cirrhosis were diagnosed, with an increasing trend in age-standardized incidence from 70.6 in 1997 to 89.6 per 100000 person-years in 2016.

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