New factors in heart failure pathophysiology: Immunity cells release of extracellular vesicles.

Front Cardiovasc Med · 2022 · PMC9669903 · PMID 36407432

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Interestingly, circulating EVs from T-lymphocytes (CD3 + /CD45 + /AV + ) significantly correlated with the cardiac damage markers hsTnT and NT-proBNP, while levels of EVs from activated neutrophils (CD29 + /CD15 + /AV + ) and hsTnT and NT-proBNP showed a trend toward significance ( Supplementary Table 4 ). cHF and control groups did not differ in the percentages of EVs shed by platelets (CD41a + ; αIIbβ3-integrin).

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