The Heterochromatin protein 1 is a regulator in RNA splicing precision deficient in ulcerative colitis.

Nat Commun · 2022 · PMC9674647 · PMID 36400769

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highly significantP Value = 10 −59actually significant

Quantifying de novo junctions revealed a highly significant increase ( P Value = 10 −59 ) in splicing noise in the UC patients, as compared to the healthy donors (Fig. 5a ).

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