Circulating miR-326 could serve as a predictive biomarker for response to neoadjuvant chemotherapy in locally advanced cervical cancer.

Discussion In a meta-analysis, NACT followed by radical surgery showed a highly significant reduction in the risk of death compared with radiotherapy alone (hazard ratio [HR] = 0.65, 95% CI [0.53, 0.8], P = 0.0004), with an absolute improvement of 14% in survival at 5 years, increasing from 50% to 64% ( 15 ).

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