Indeed, formal testing of the different edited loci into the five classes of DNA mutations indicated that the highly significant association between the loci and DNA mutation outcomes, indicating a non-random association between repair mutation outcome and specific loci (Fisher’s exact test, two-sided, p -value = 0.0009995).
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CRISPR-Cas12a induced DNA double-strand breaks are repaired by multiple pathways with different mutation profiles in Magnaporthe oryzae.
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