A history of childhood maltreatment is associated with altered DNA methylation levels of DNA methyltransferase 1 in maternal but not neonatal mononuclear immune cells.

Front Psychiatry · 2022 · PMC9685310 · PMID 36440389

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0.0860

closest p · 1.7× alpha

0.0860

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The sentences

a trend toward significancep = 0.086so close (0.05 < p ≤ 0.1)

The association between DNA methyltransferase 1 and NR3C1 in peripheral blood mononuclear cells There was no significant correlation between DNMT1 and NR3C1 exon 1F mean DNAm ( r s = 0.031, p = 0.752, Figure 3A ), but a trend toward significance between DNMT1 mean DNAm and NR3C1 relative gene expression ( r s = 0.215, p = 0.086).

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