Di-(2-ethylhexyl) phthalate exposure induces liver injury by promoting ferroptosis <i>via</i> downregulation of GPX4 in pregnant mice.

Front Cell Dev Biol · 2022 · PMC9686828 · PMID 36438553

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an increasing trendno p-value reported

Compared with the 1,000 mg/kg DEHP-espoused group, the mRNA level of Slc7a11 was significantly increased and Ptgs2 was obviously decreased ( p < 0.05), while the expression of Nrf2 and Gpx4 showed an increasing trend that was not significantly different in the DEHP + Fer-1 group ( Figures 5A–D ).

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