Inhibition of Wdr5 Attenuates Ang-II-Induced Fibroblast-to-Myofibroblast Transition in Cardiac Fibrosis by Regulating Mdm2/P53/P21 Pathway.

Biomolecules · 2022 · PMC9687631 · PMID 36358925

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may not be significantno p-value reported

The Wdr5 inhibitor significantly decreased cardiac fibrosis, given the still high blood pressure and the short duration of medication, the effect on cardiac function may not be significant.

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