extremely significantp < 0.01
We found that IPRS-low patients had significantly higher CYT, GEP, and MHC scores than others (Wilcoxon test p < 0.01, Figure 5 I–K); meanwhile, extremely significant negative associations were observed between the IPRS and three immune-related scores (Pearson correlation test p < 0.01, Figure 5 L–N).