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The Dual PDE7-GSK3β Inhibitor, VP3.15, as Neuroprotective Disease-Modifying Treatment in a Model of Primary Progressive Multiple Sclerosis.

Int J Mol Sci · 2022 · PMC9694690 · PMID 36430856

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highly significantno p-value reported
Importantly, TMEV infection affects the differentiation of OPCs, showing a highly significant decrease in mature oligodendrocytes with myelinating capacity [ 23 ], something that in our case, was seen counteracted with by the administration of VP3.15.

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