Analysis of Exosomal MicroRNA Dynamics in Response to Rhinovirus Challenge in a Longitudinal Case-Control Study of Asthma.

Instead, the Downregulated Cluster miRNAs had an upregulated mean expression on day 1 post RV challenge and then had a decreasing trend up to day 6 following RV challenge in asthmatic subjects indicating two distinct classes of miRNA dynamics.

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In the Upregulated Cluster, the mean miRNA expression level in asthmatics was initially downregulated on day 1 post RV challenge compared to their healthy counterparts, and then had an increasing trend up to day 9 following RV challenge.

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