circCsnk1g3- and circAnkib1-regulated interferon responses in sarcoma promote tumorigenesis by shaping the immune microenvironment.

Nat Commun · 2022 · PMC9700836 · PMID 36433954

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a decreasing trendno p-value reported

By comparing the relative abundance of these cell types across conditions, we found that silencing of circCsnk1g3 was associated with a decreasing trend for regulatory T cells (Treg) and exhausted CD8+ T cells; conversely, cytotoxic CD8+ T cells showed the opposite trend (Fig. 4e ).

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