Hepatic mRNA levels of actin alpha 2, smooth muscle ( Acta2 ) showed an increasing trend while the mRNA levels of collagen type I alpha 2 ( Col1a2 ) and Col3a1 tended to decrease in Phb1 adipo−/− mice compared to WT mice under the HFD, as illustrated in Figure 6D .
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Deletion of adipocyte prohibitin 1 exacerbates high-fat diet-induced steatosis but not liver inflammation and fibrosis.
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