Genetic/Environmental Contributions and Immune Dysregulation in Children with Atopic Dermatitis.

J Asthma Allergy · 2022 · PMC9701514 · PMID 36447957

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highly significantno p-value reported

149 GWAS has identified two highly significant loci for AD representing the EDC (chromosome 1q21.3) and a region including IL4 and IL13 (chromosome 5q13.1). 150 Chromosome 11q13.5 is another locus that has been strongly linked to AD in GWAS among different ethnicities and suggests LRRC32 and EMSY as possible players in AD. 51 , 150 Among Caucas

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