Whole genome sequencing reveals epistasis effects within RET for Hirschsprung disease.

Sci Rep · 2022 · PMC9705416 · PMID 36443333

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marginally significantno p-value reported

The other variant rs7069590 ( RET-5.5 ) highlighted in their study shows a significant marginal association (p = 9.01 × 10 –8 ) but this variant is no longer marginally significant after conditioning on the lead variant (see Fig. 2 ).

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