SRSF1 acts as an IFN-I-regulated cellular dependency factor decisively affecting HIV-1 post-integration steps.

Front Immunol · 2022 · PMC9706209 · PMID 36458014

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highly significantno p-value reported

Treatment with IFNα2 resulted in a 13-fold and highly significant downregulation of SRSF1 after 12 h while expression levels were restored (less than twofold) 24–48 h post-treatment ( Figure 4A , right panel).

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