Loss of NDR1/2 kinases impairs endomembrane trafficking and autophagy leading to neurodegeneration.

Life Sci Alliance · 2023 · PMC9711861 · PMID 36446521

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not yet significantno p-value reported

On Western blots, it became evident that at P20 the increase in p62 is not yet significant, but by 6 wk of age significantly more p62 is present in NDR1/2 KO brains ( Fig 4B ), indicative of a gradual age-dependent upregulation in this marker.

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