Bioinformatics-based study reveals that AP2M1 is regulated by the circRNA-miRNA-mRNA interaction network and affects Alzheimer's disease.

Front Genet · 2022 · PMC9716081 · PMID 36468008

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In particular, the alteration of the structural and functional phenotype of the presynaptic terminal is highly significant evidence for neural diseases, including Alzheimer’s disease (AD), Parkinson’s disease (PD), Amyotrophic lateral sclerosis ( ALS ), and Huntington’s disease (HD) ( Bae and Kim, 2017 ; Ovsepian et al., 2018 ).

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