Examining the list of GO terms for evidence of cascades of downregulated mRNAs following 5′ isomiR transfection, the type I interferon (IFNA/IFNB) and interferon gamma (IFNG) pathways turned up as highly significant.
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Extensive downregulation of immune gene expression by microRNA-140-3p 5' isomiR in an in vitro model of osteoarthritis.
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