By combining blood metabolomics and transcriptomics data within the same cohort, the authors identified glycerophospholipids, an important component of lung surfactant, along with the lipid classes lysophosphatidylethanolamine (LysoPE) and phosphatidylglycerol (PG) as highly significant in relation to FEV 1 % pred, and sphingolipids to be associated with FEV 1 /FVC [ 58 ].
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Air pollution, metabolites and respiratory health across the life-course.
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