Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer.

Cell Rep Med · 2022 · PMC9729824 · PMID 36384095

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not yet significantno p-value reported

Our results show that 18 F-FDG uptake is readily detected by PET-CT scan of subcutaneously implanted KCP tumors and that a significant decrease in PET signal is already observable at a time when reduction in tumor volume is not yet significant ( Figure 7 ).

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