Retroviral Replicating Vector Toca 511 (<i>Vocimagene Amiretrorepvec</i>) for Prodrug Activator Gene Therapy of Lung Cancer.

In contrast, Toca 511-transduced subcutaneous tumors treated with 5-FC showed highly significant growth inhibition compared to PBS-treated controls ( p = 0.0051 in A549 model ( Figure 4 A), p = 0.0018 in Ex-3LL model ( Figure 4 B).

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