Barely Significant
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Irrespective of Plaque Activity, Multiple Sclerosis Brain Periplaques Exhibit Alterations of Myelin Genes and a TGF-Beta Signature.

Int J Mol Sci · 2022 · PMC9738407 · PMID 36499320

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highly significantno p-value reported
We reported that a highly significant number of genes that were co-downregulated with NDRG1 in SC periplaques are involved in the translation machinery [ 13 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.