LINE-1 hypomethylation is associated with poor outcomes in locoregionally advanced oropharyngeal cancer.

Clin Epigenetics · 2022 · PMC9743592 · PMID 36503584

Europe PMC DOI

hedged sentence

0.0040

closest p · 0.1× alpha

0.0040

boldest claim

The sentences

of borderline significancep = 0.004actually significant

Only PIK3C2G cg17881542 was present in this dataset and, although the data were of borderline significance (log-rank test, p = 0.004; HR = 0.77, 95% CI 0.59–1.01), we could observe that high methylation levels of cg17881542 were associated with favorable prognosis in HNSCC (Fig. 5 b).

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