Global, regional, and national burden and attributable risk factors of neurological disorders: The Global Burden of Disease study 1990-2019.

Front Public Health · 2022 · PMC9745318 · PMID 36523572

Europe PMC DOI

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closest p · 1.0× alpha

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an increasing trendP < 0.05actually significant

Comparing the Joinpoint regression results of risk factors, it was observed that the attribution of high body-mass index to the age-standardized DALY rate showed an increasing trend in recent years (Annual Percent Change, APC = 0.25, P < 0.05) ( Supplementary Figure S1 ).

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a decreasing trendno p-value reported

Neural tube defects Neural tube defects caused 7,743.43 (95%UI 5,726.20, 11,022.80) thousands DALYs in 2019, which showed a decreasing trend of 47.1% (95%UI 32.40, 58.29) from 1990 to 2019.

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