Real-world Evidence of the Effects of Novel Treatments for COVID-19 on Mortality: A Nationwide Comparative Cohort Study of Hospitalized Patients in the First, Second, Third, and Fourth Waves in the Netherlands.

Open Forum Infect Dis · 2022 · PMC9745783 · PMID 36519114

Europe PMC DOI

hedged sentence

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

a positive trendP = .057so close (0.05 < p ≤ 0.1)

The crude in-hospital mortality of ward patients decreased from 21% (n = 510) in wave 1 to 15% (n = 74) in wave 4 ( P < .001), while the crude ICU mortality in patients first admitted to the ward showed a positive trend (29%, n = 88, in wave 1 to 16%, n = 14, in wave 4; P = .057) ( Table 1 ).

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