Association between loneliness and its components and cognitive function among older Chinese adults living in nursing homes: A mediation of depressive symptoms, anxiety symptoms, and sleep disturbances.

A significant inverse association was observed for the personal feelings of isolation, and a marginally significant inverse association was also seen for the component of the lack of relational connectedness, with the multivariable-adjusted β coefficients (95% CIs) of -1.26 (-2.22 to -0.31) and -0.93 (-1.87 to 0.00) for the high group compared with the low group, respectively.

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First, the sample size of the present study was relatively small, which may have contributed to the instability of the 95% CIs of the regression coefficient estimates and can account for the borderline significance of the association for the loneliness component of the lack of relational connectedness.

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