Effect of difference between EV-A71 virus epidemic strain and "vaccine strain" on neutralizing antibody titer.

Hum Vaccin Immunother · 2022 · PMC9746541 · PMID 36112355

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a decreasing trendno p-value reported

For “vaccine strain,” the seropositivity rates and higher NtAb titer ranges showed a decreasing trend with age, indicating that younger people are being continuously exposed to EV-A71 over time, and they often experience repetitive infections.

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