Targeting TNF-α-producing macrophages activates antitumor immunity in pancreatic cancer via IL-33 signaling.

JCI Insight · 2022 · PMC9746819 · PMID 36256464

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a nonsignificant trendno p-value reported

20%) and a nonsignificant trend of decreasing lung metastasis (41% vs. 30%).

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a decreasing trendno p-value reported

Notably, we also observed a concerning trend of increased diaphragm metastasis in the Gem+ICB, but a decreasing trend in the Gem+ICB+CCR2i cohort ( Figure 7F ).

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