SLC11A1 as a stratification indicator for immunotherapy or chemotherapy in patients with glioma.

Consistent with the above results, based on the analysis of GEO dataset analysis, the GSE16011 dataset showed an increasing trend in the number of patients with high-grade glioma ( Figure 4E ); similar results were observed for the GSE4412 dataset ( Figure 4F ) and the GSE43289 dataset ( Figure 4G ). qRT–PCR and immunohistochemistry (IHC) staining for SLC11A1 were used to evaluate SLC11A1 expression in tumor tissue samples and for further validation.

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