The study suggested that polymorphism at promotor region and two non-synonymous polymorphism of MMP-8 may not be significant in mediating risk of developing oral cancer in Taiwanese population. 11 Pradhan-Palikhe et al implied that patient’s survival is improved via MMP-8 expression by tumour cells as well as carcinogenesis is protected by MMP-8 from OTSCC. 29 No significant association between MMP-8 and lymph nodes metastasis has been reported. 30 Contrary to the results of this study, Kuropkat et al found elevated levels of serum MMP-8 of head and neck cancer patients compared with healthy participants.
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Relation of salivary MMP-8 with oral submucous fibrosis and oral squamous cell carcinoma: a cross sectional analytical study.
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