Association of parental HLA-G polymorphisms with soluble HLA-G expressions and their roles on recurrent implantation failure: A systematic review and meta-analysis.

Front Immunol · 2022 · PMC9751038 · PMID 36532068

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extremely significantp-value<0.01actually significant

Meta-analysis showed that maternal circulating sHLA-G concentration was not significantly associated with RIF (SMD -0.81, 95%CI -2.84~-1.21, p-value=0.432) with extremely significant heterogeneity (I 2 = 95.4%, p-value<0.01) ( Figure 6 and Supplementary Table 6 ).

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