extremely significantp< 0.001
highly significantp< 0.01
The difference is denoted in four levels, significant *p< 0.05, highly significant **p< 0.01, extremely significant ***p< 0.001, and highly extremely significant ****p< 0.0001.TBtools ( Chen et al., 2020 ), SPSS22.0, and GraphPad Prism (GraphPad Prism 8; GraphPad) were used to analyze and plot the data.