Subcellular location of source proteins improves prediction of neoantigens for immunotherapy.

Unlike having parent proteins in a location previously associated with immunogenic peptides, the number of MHC‐eluted peptides from neopeptide parent proteins alone did not correlate with immune response, although there was a weak trend for neopeptide parent proteins exclusive to MHC‐II to have higher numbers of eluted peptides observed (Appendix Fig S14 B).

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