Climate and socio-economic factors drive the spatio-temporal dynamics of HFRS in Northeastern China.

Additionally, HFRS mainly presented a decreasing trend from 2001 to 2019 in most areas of Northeastern China, but slightly increased in the cities of Daqing, Songyuan, Baicheng, and Tonghua.

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Some prefecture-level cities such as Daqing and Song Yuan showed an increasing trend of HFRS in the past 19 years, which suggests that special attention should be paid and more public health resources must be mobilized toward this region.

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