Potential effect of pulmonary fluid viscosity on positive end-expiratory pressure and regional distribution of lung ventilation in acute respiratory distress syndrome.

As was expected, the correlation between the viscosity and product of applied PEEP and FiO 2 was highly significant and almost close to identity (R 2 = 0.9837, p = 0.0082 and R 2 = 0.9955, p = 0.0023 in patents 7 and 8, respectively).

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3 ) did not show an increasing trend over time, and therefore we speculated that the opening of more airways or lung units may be attributed to a decrease of critical airway or alveolar opening pressure, which in turn depends on viscosity and surface tension of pulmonary fluids ( Chen et al., 2015 ; Gaver et al., 1990 ; Gaver et al., 2006 ).

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