The second highly significant difference affects the nasal samples where Dolosigranulum pigrum is associated with DCD-WT and Bosea vestrisii with DCD-MT. 4 Discussion HS is an autoinflammatory skin disease with a multifactorial aetiology that involves a strict interplay between genetic factors, immune dysregulation and lifestyle factors.
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A rare loss-of-function genetic mutation suggest a role of dermcidin deficiency in hidradenitis suppurativa pathogenesis.
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