A Clinical Study Provides the First Direct Evidence That Interindividual Variations in Fecal β-Lactamase Activity Affect the Gut Mycobiota Dynamics in Response to β-Lactam Antibiotics.

mBio · 2022 · PMC9765473 · PMID 36448778

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highly significantno p-value reported

Finally, we showed a highly significant negative interaction between the D0 to D10 AUC of the change in β-lactamase activity and the D0 to D10 AUC of the change in C. albicans DNA levels (Spearman correlation; R: −0.59, P value: 0.009; Fig. 3D ).

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