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Investigating neurological symptoms of infectious diseases like COVID-19 leading to a deeper understanding of neurodegenerative disorders such as Parkinson's disease.

Front Neurol · 2022 · PMC9768197 · PMID 36570463

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an increasing trendno p-value reported
In addition, since (1) a number of COVID-19 symptoms (loss of sense of smell, taste impairment, dizziness, etc.) and long COVID symptoms (cognitive impairment, tremors, functional mobility impairment, gastrointestinal problems, sleep disorder, etc.) ( 13 , 33 – 35 ) overlap with symptoms of PD or parkinsonism, (2) the evidence of the COVID-associated acute parkinsonism cases ( 16 – 22 ), the 260 (0.11%) post-COVID-19 parkinsonism cases ( 1 ), high percentages of functional mobility impairment (44%) and mobility decline (20.2%) in long COVID ( 13 ), and an increasing trend of motor symptoms like tremors ( 35 ) among patients with long COVID has suggested that SARS-CoV-2 infection may trigger (acute or chronic) neural injury in the nigrostriatal system, a long lasting neuroinflammation and subsequent motor-associated neurodegeneration, (3) there are much similarities

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