While the second periplasmic domain of GlnX matches CHASE3, albeit with borderline significance (E value, 9.5 × 10 −5 ), no match was found for the first periplasmic domain, indicating that its sequence has further diverged from the presumed common 4HB ancestor while the characteristic three-dimensional fold was preserved.
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Characteristics of the GlnH and GlnX Signal Transduction Proteins Controlling PknG-Mediated Phosphorylation of OdhI and 2-Oxoglutarate Dehydrogenase Activity in Corynebacterium glutamicum.
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