, increased proportion of actives discovered). Interestingly, there also seems to be a small trend of increasing the average molecular weight of the compounds, but the lipophilicity, topological polar surface area (TPSA), and the number of hydrogen-bond donors and acceptors seem to remain stable (see Figure S1 ).
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Exploring the Chemical Space of Urease Inhibitors to Extract Meaningful Trends and Drivers of Activity.
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