Recent Advances in Electrochemical Biosensors for Monitoring Animal Cell Function and Viability.

In the lung cancer models, the maximal drug efficacy of all tested concentrations of cisplatin is evaluated; extremely significant differences are identified between the 2D ECIS (10 μM: 77.11% ± 0.58%; 100 μM: 80.67% ± 0.88%; 1000 μM: 84.69% ± 0.89%) and the 3D ECIS (10 μM: 30.44% ± 0.87%; 100 μM: 44.38% ± 2.03%; 1000 μM: 57.73% ± 0.89%; Figure 5 B) because the 2D cells lack an extracellular matrix and intercellular connections occur in the 3D in vivo environment.

also in 7,787 other papers