Multifaceted functions of STING in human health and disease: from molecular mechanism to targeted strategy.

Signal Transduct Target Ther · 2022 · PMC9780328 · PMID 36550103

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an obvious trendno p-value reported

62 As seen in the clinical trials of STING-based therapies (Table 4 ), an obvious trend is the combined therapy with immune checkpoint inhibitors, including programmed death-1/ programmed death-ligand 1 (PD-1/PD-L1) blocking antibody and cytotoxic T-lymphocyte antigen 4 (CTLA-4) blocking antibody.

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