Epigenome-wide meta-analysis identifies DNA methylation biomarkers associated with diabetic kidney disease.

Nat Commun · 2022 · PMC9780337 · PMID 36550108

Europe PMC DOI

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highly significantp < 2.2 × 10 −308actually significant

These included four differentially methylated CpGs associated with eGFR; a highly significant cg21961721 within SLC27A3 ( p < 2.2 × 10 −308 ), two intergenic CpGs between ZNF788P and ZNF625-ZNF20 (cg17944885; p = 3.7 × 10 −13 and cg25544931; p = 2.1 × 10 −5 ), and cg05165263 within the IRF2 gene ( p = 6.6 × 10 −5 ).

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