Mediterranean diet score is associated with greater allocentric processing in the EPAD LCS cohort: A comparative analysis by biogeographical region.

A randomized control trial that allocated participants in the USA with normal cognition and MCI to either the MedDiet or Western diet found a borderline significant interaction between diet, diagnosis and time for the cognitive composite, however no individual comparisons between the groups were significant for the cognitive outcome ( Hoscheidt et al., 2021 ).

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The association between higher MedDiet adherence, as measured by the MEDAS score, and higher FMT scores remained marginally significant in both the Mediterranean region (Unadjusted model β: 0.21, SE: 0.07, p : 0.005; Fully adjusted model β: 0.14, SE: 0.07, p : 0.049) and the non-Mediterranean region in the fully adjusted model (Unadjusted model β: 0.14, SE: 0.06, p : 0.01; Fully adjusted model β: 0.11, SE: 0.05, p : 0.45).

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