borderline significantp = 0.051
Liquid penetration was slower at higher compaction pressures, and this was found to be significant for preheated tablets with SSG ( p < 0.001), but only borderline significant for those with XPVP ( p = 0.051).
Liquid penetration was slower at higher compaction pressures, and this was found to be significant for preheated tablets with SSG ( p < 0.001), but only borderline significant for those with XPVP ( p = 0.051).
Similarly, the intra-oral temperature has also been found to vary considerably (18.9 to 48.4 °C) with meal temperatures [ 41 ], suggesting that the effect of the disintegration medium temperature may be significant for orodispersible tablets as well.