Impact of Cabozantinib Exposure on Proteinuria and Muscle Toxicity in Patients with Unresectable Hepatocellular Carcinoma.

Although there was no significant association between maximum changes in UPCR and maximum C trough ( r = 0.368, p = 0.216) ( Figure 3 D), highly significant statistical correlations were observed between both maximum changes in serum creatine kinase and aldolase values during treatment and maximum C trough ( r = 0.736, p < 0.01; r = 0.798, p < 0.001, respectively) ( Figure 3 E,F). 2.6.

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